LncRNA ANRIL acts as a modular scaffold of WDR5 and HDAC3 complexes and promotes alteration of the vascular smooth muscle cell phenotype

Many studies have shown that long-noncoding RNA (lncRNA) is associated with cardiovascular disease, but its molecular mechanism is still unclear. In this study, we explored the role of lncRNA ANRIL in ox-LDL-induced phenotypic transition of human aortic smooth muscle cells (HASMC). The results of qu...

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Detalles Bibliográficos
Autores principales: Zhang, Chengxin, Ge, Shangqing, Gong, Wenhui, Xu, Jinguo, Guo, Zhixiang, Liu, Zhuang, Gao, Xiaotian, Wei, Xiaoyong, Ge, Shenglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280314/
https://www.ncbi.nlm.nih.gov/pubmed/32513988
http://dx.doi.org/10.1038/s41419-020-2645-3

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