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Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. Inflammatory pathways contribute to disease pathogenesis; however, regulation of the underlying mechanism is not completely understood. IL-1β, a pro-inflammatory cytokine, participates in the development and...
Autores principales: | Mirea, Andreea-Manuela, Stienstra, Rinke, Kanneganti, Thirumala-Devi, Tack, Cees J., Chavakis, Triantafyllos, Toonen, Erik J.M., Joosten, Leo A.B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280336/ https://www.ncbi.nlm.nih.gov/pubmed/32002713 http://dx.doi.org/10.1007/s10753-020-01190-4 |
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