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3-Amidinophenylalanine-derived matriptase inhibitors can modulate hepcidin production in vitro

Matriptase-2 (MT-2) is a type II transmembrane serine protease and predominantly attached to the surface of hepatocytes. MT-2 decreases the production of hepcidin, a key regulator of iron homeostasis. In this study, the effects of four 3-amidinophenylalanine-derived combined matriptase-1/matriptase-...

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Detalles Bibliográficos
Autores principales:	Pászti-Gere, Erzsébet, Szombath, Gergely, Gütschow, Michael, Steinmetzer, Torsten, Székács, András
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280348/ https://www.ncbi.nlm.nih.gov/pubmed/31659405 http://dx.doi.org/10.1007/s00210-019-01743-x

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