Magnetic and near-infrared derived heating characteristics of dimercaptosuccinic acid coated uniform Fe@Fe(3)O(4) core–shell nanoparticles

Among the number of hyperthermia materials, magnetic nanoparticles have received much attention. In this work, we studied the heating characteristics of uniform Fe@Fe(3)O(4) core–shell nanoparticle under near-infrared laser irradiation and external AC magnetic field applying. The Fe@Fe(3)O(4) core–shell nanoparticles were prepared by thermal decomposition of iron pentacarbonyl and followed by controlled oxidation. The prepared uniform particles were further coated with dimercaptosuccinic acid to make them well dispersed in water. Near-infrared derived photothermal study of solutions containing a different concentration of the core–shell nanoparticles was made by using 808 nm laser Source. Additionally, magnetic hyperthermia ability of the Fe@Fe(3)O(4) nanoparticle at 150 kHz and various oersted (140–180 Oe) condition was systemically characterized. The Fe@Fe(3)O(4) nanoparticles which exhibited effective photo and magnetic hyperthermia are expected to be used in biomedical application.