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Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy
The integrated stress response is characterized by the phosphorylation of eukaryotic initiation factor-2α (eIF2α) on serine 51 by one out of four specific kinases (EIF2AK1 to 4). Here we provide three series of evidence suggesting that macroautophagy (to which we refer to as autophagy) induced by a...
Autores principales: | Humeau, Juliette, Leduc, Marion, Cerrato, Giulia, Loos, Friedemann, Kepp, Oliver, Kroemer, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280501/ https://www.ncbi.nlm.nih.gov/pubmed/32513922 http://dx.doi.org/10.1038/s41419-020-2642-6 |
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