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SARS‐CoV‐2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection
An ongoing outbreak of viral pneumonia was caused by a novel coronavirus in China in 2019. By March 19, over 200 thousand confirmed cases of SARS‐CoV‐2 infection and over 9000 deaths have been reported throughout the world. For this infectious disease, nucleic acid detection is still the gold standa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280606/ https://www.ncbi.nlm.nih.gov/pubmed/32431052 http://dx.doi.org/10.1111/jcmm.15275 |
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author | Li, Hua Pan, Jue Su, Yi Wang, Beili Ge, Junbo |
author_facet | Li, Hua Pan, Jue Su, Yi Wang, Beili Ge, Junbo |
author_sort | Li, Hua |
collection | PubMed |
description | An ongoing outbreak of viral pneumonia was caused by a novel coronavirus in China in 2019. By March 19, over 200 thousand confirmed cases of SARS‐CoV‐2 infection and over 9000 deaths have been reported throughout the world. For this infectious disease, nucleic acid detection is still the gold standard for pathogenic detection. However, nucleic acid detection takes a long time and has relatively high "false negative"; therefore, we need urgently a convenient and accurate detection method to make up for this deficiency. In this article, we will show such technical characteristics of lgM/lgG serum antibody detection, compared with nucleic acid detection. |
format | Online Article Text |
id | pubmed-7280606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72806062020-06-09 SARS‐CoV‐2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection Li, Hua Pan, Jue Su, Yi Wang, Beili Ge, Junbo J Cell Mol Med Short Communications An ongoing outbreak of viral pneumonia was caused by a novel coronavirus in China in 2019. By March 19, over 200 thousand confirmed cases of SARS‐CoV‐2 infection and over 9000 deaths have been reported throughout the world. For this infectious disease, nucleic acid detection is still the gold standard for pathogenic detection. However, nucleic acid detection takes a long time and has relatively high "false negative"; therefore, we need urgently a convenient and accurate detection method to make up for this deficiency. In this article, we will show such technical characteristics of lgM/lgG serum antibody detection, compared with nucleic acid detection. John Wiley and Sons Inc. 2020-05-19 2020-07 /pmc/articles/PMC7280606/ /pubmed/32431052 http://dx.doi.org/10.1111/jcmm.15275 Text en © 2020 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Communications Li, Hua Pan, Jue Su, Yi Wang, Beili Ge, Junbo SARS‐CoV‐2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection |
title | SARS‐CoV‐2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection |
title_full | SARS‐CoV‐2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection |
title_fullStr | SARS‐CoV‐2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection |
title_full_unstemmed | SARS‐CoV‐2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection |
title_short | SARS‐CoV‐2 lgM/lgG antibody detection confirms the infection after three negative nucleic acid detection |
title_sort | sars‐cov‐2 lgm/lgg antibody detection confirms the infection after three negative nucleic acid detection |
topic | Short Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280606/ https://www.ncbi.nlm.nih.gov/pubmed/32431052 http://dx.doi.org/10.1111/jcmm.15275 |
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