Prioritization of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics

There is a rapidly expanding literature on the in vitro antiviral activity of drugs that may be repurposed for therapy or chemoprophylaxis against severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2). However, this has not been accompanied by a comprehensive evaluation of the target plasma a...

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Detalles Bibliográficos
Autores principales: Arshad, Usman, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith K. R., Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steve P., O’Neill, Paul M., Aljayyoussi, Ghaith, Pennington, Shaun H., Ward, Stephen A., Hill, Andrew, Back, David J., Khoo, Saye H., Bray, Patrick G., Biagini, Giancarlo A., Owen, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280633/
https://www.ncbi.nlm.nih.gov/pubmed/32438446
http://dx.doi.org/10.1002/cpt.1909

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