Cargando…
γδ TCR Recognition of MR1: Adapting to Life on the Flip Side
Nonclassical class I MHC-like molecules are ligands for several unconventional T cell populations. Recently, Le Nours et al. identified human γδ T cells recognising MHC-related protein-1 (MR1) via their T cell receptor (TCR). Also recognised by the αβ-TCR of mucosal associated invariant T cells, MR1...
Autores principales: | Willcox, Benjamin E., Mohammed, Fiyaz, Willcox, Carrie R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Trends Journals
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280785/ https://www.ncbi.nlm.nih.gov/pubmed/32299647 http://dx.doi.org/10.1016/j.tibs.2020.03.012 |
Ejemplares similares
-
Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
por: Davey, Martin S., et al.
Publicado: (2017) -
Modifications outside CDR1, 2 and 3 of the TCR variable β domain increase TCR expression and antigen-specific function
por: Degirmencay, Abdullah, et al.
Publicado: (2023) -
Division of labor and cooperation between different butyrophilin proteins controls phosphoantigen-mediated activation of human γδ T cells
por: Karunakaran, Mohindar Murugesh, et al.
Publicado: (2023) -
Human liver infiltrating γδ T cells are composed of clonally expanded circulating and tissue-resident populations
por: Hunter, Stuart, et al.
Publicado: (2018) -
Recasting Human Vδ1 Lymphocytes in an Adaptive Role
por: Davey, Martin S., et al.
Publicado: (2018)