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Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging

STUDY DESIGN: Observational study. PURPOSE: To evaluate healthy volunteers and patients with spinal canal lesions using apparent diffusion coefficient (ADC) maps with diffusion-weighted imaging. OVERVIEW OF LITERATURE: Decompression surgery for lumbar spinal stenosis (LSS) is selected on the basis o...

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Autores principales: Kanamoto, Hirohito, Norimoto, Masaki, Eguchi, Yawara, Oikawa, Yasuhiro, Orita, Sumihisa, Inage, Kazuhide, Abe, Koki, Inoue, Masahiro, Kinoshita, Hideyuki, Umimura, Tomotaka, Matsumoto, Koji, Masuda, Yoshitada, Furuya, Takeo, Koda, Masao, Aoki, Yasuchika, Watanabe, Atsuya, Takahashi, Kazuhisa, Ohtori, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Spine Surgery 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280930/
https://www.ncbi.nlm.nih.gov/pubmed/32050309
http://dx.doi.org/10.31616/asj.2019.0266
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author Kanamoto, Hirohito
Norimoto, Masaki
Eguchi, Yawara
Oikawa, Yasuhiro
Orita, Sumihisa
Inage, Kazuhide
Abe, Koki
Inoue, Masahiro
Kinoshita, Hideyuki
Umimura, Tomotaka
Matsumoto, Koji
Masuda, Yoshitada
Furuya, Takeo
Koda, Masao
Aoki, Yasuchika
Watanabe, Atsuya
Takahashi, Kazuhisa
Ohtori, Seiji
author_facet Kanamoto, Hirohito
Norimoto, Masaki
Eguchi, Yawara
Oikawa, Yasuhiro
Orita, Sumihisa
Inage, Kazuhide
Abe, Koki
Inoue, Masahiro
Kinoshita, Hideyuki
Umimura, Tomotaka
Matsumoto, Koji
Masuda, Yoshitada
Furuya, Takeo
Koda, Masao
Aoki, Yasuchika
Watanabe, Atsuya
Takahashi, Kazuhisa
Ohtori, Seiji
author_sort Kanamoto, Hirohito
collection PubMed
description STUDY DESIGN: Observational study. PURPOSE: To evaluate healthy volunteers and patients with spinal canal lesions using apparent diffusion coefficient (ADC) maps with diffusion-weighted imaging. OVERVIEW OF LITERATURE: Decompression surgery for lumbar spinal stenosis (LSS) is selected on the basis of subjective assessment and cross-sectional magnetic resonance imaging (MRI). However, there is no objective standard for this procedure. METHODS: We performed 3T MRI in 10 healthy volunteers and 13 patients with LSS. The ADC values in the spinal canal were evaluated at 46 vertebrae (L4/5 and L5/S1 for each participant), and the reduced and conventional fields of view were compared. RESULTS: The ADC values were 2.72±0.12 at L4/5 in healthy volunteers, 2.76±0.19 at L5/S1 in healthy volunteers, 1.77±0.58 at L4/5 in patients with LSS, and 2.35±0.29 at L5/S1 in patients with LSS. The ADC value at L4/5 in patients with LSS was significantly lower than that at L5/S1 in patients with LSS and that at L4/5 and L5/S1 in healthy volunteers (p <0.05). With an ADC cutoff value of 2.46 to identify LSS, this approach provided an area under the curve of 0.81, sensitivity of 0.92, and specificity of 0.76 (p <0.05). CONCLUSIONS: Preoperative examination using ADC maps permits visualization and quantification of spinal canal lesions, thus proving the utility of ADC maps in the selection of decompression surgery for LSS.
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spelling pubmed-72809302020-06-17 Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging Kanamoto, Hirohito Norimoto, Masaki Eguchi, Yawara Oikawa, Yasuhiro Orita, Sumihisa Inage, Kazuhide Abe, Koki Inoue, Masahiro Kinoshita, Hideyuki Umimura, Tomotaka Matsumoto, Koji Masuda, Yoshitada Furuya, Takeo Koda, Masao Aoki, Yasuchika Watanabe, Atsuya Takahashi, Kazuhisa Ohtori, Seiji Asian Spine J Clinical Study STUDY DESIGN: Observational study. PURPOSE: To evaluate healthy volunteers and patients with spinal canal lesions using apparent diffusion coefficient (ADC) maps with diffusion-weighted imaging. OVERVIEW OF LITERATURE: Decompression surgery for lumbar spinal stenosis (LSS) is selected on the basis of subjective assessment and cross-sectional magnetic resonance imaging (MRI). However, there is no objective standard for this procedure. METHODS: We performed 3T MRI in 10 healthy volunteers and 13 patients with LSS. The ADC values in the spinal canal were evaluated at 46 vertebrae (L4/5 and L5/S1 for each participant), and the reduced and conventional fields of view were compared. RESULTS: The ADC values were 2.72±0.12 at L4/5 in healthy volunteers, 2.76±0.19 at L5/S1 in healthy volunteers, 1.77±0.58 at L4/5 in patients with LSS, and 2.35±0.29 at L5/S1 in patients with LSS. The ADC value at L4/5 in patients with LSS was significantly lower than that at L5/S1 in patients with LSS and that at L4/5 and L5/S1 in healthy volunteers (p <0.05). With an ADC cutoff value of 2.46 to identify LSS, this approach provided an area under the curve of 0.81, sensitivity of 0.92, and specificity of 0.76 (p <0.05). CONCLUSIONS: Preoperative examination using ADC maps permits visualization and quantification of spinal canal lesions, thus proving the utility of ADC maps in the selection of decompression surgery for LSS. Korean Society of Spine Surgery 2020-06 2020-02-14 /pmc/articles/PMC7280930/ /pubmed/32050309 http://dx.doi.org/10.31616/asj.2019.0266 Text en Copyright © 2020 by Korean Society of Spine Surgery This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Kanamoto, Hirohito
Norimoto, Masaki
Eguchi, Yawara
Oikawa, Yasuhiro
Orita, Sumihisa
Inage, Kazuhide
Abe, Koki
Inoue, Masahiro
Kinoshita, Hideyuki
Umimura, Tomotaka
Matsumoto, Koji
Masuda, Yoshitada
Furuya, Takeo
Koda, Masao
Aoki, Yasuchika
Watanabe, Atsuya
Takahashi, Kazuhisa
Ohtori, Seiji
Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging
title Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging
title_full Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging
title_fullStr Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging
title_full_unstemmed Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging
title_short Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging
title_sort evaluating spinal canal lesions using apparent diffusion coefficient maps with diffusion-weighted imaging
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280930/
https://www.ncbi.nlm.nih.gov/pubmed/32050309
http://dx.doi.org/10.31616/asj.2019.0266
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