Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine

The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute...

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Autores principales: Lombardo, Morgan, DiPiazza, Amanda, Rippey, Kelly, Lubarr, Naomi, Clar, Elana, Azmi, Hooman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Movement Disorder Society 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280942/
https://www.ncbi.nlm.nih.gov/pubmed/32498499
http://dx.doi.org/10.14802/jmd.20005
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author Lombardo, Morgan
DiPiazza, Amanda
Rippey, Kelly
Lubarr, Naomi
Clar, Elana
Azmi, Hooman
author_facet Lombardo, Morgan
DiPiazza, Amanda
Rippey, Kelly
Lubarr, Naomi
Clar, Elana
Azmi, Hooman
author_sort Lombardo, Morgan
collection PubMed
description The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.
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spelling pubmed-72809422020-06-17 Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine Lombardo, Morgan DiPiazza, Amanda Rippey, Kelly Lubarr, Naomi Clar, Elana Azmi, Hooman J Mov Disord Case Report The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours. The Korean Movement Disorder Society 2020-05 2020-05-29 /pmc/articles/PMC7280942/ /pubmed/32498499 http://dx.doi.org/10.14802/jmd.20005 Text en Copyright © 2020 The Korean Movement Disorder Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lombardo, Morgan
DiPiazza, Amanda
Rippey, Kelly
Lubarr, Naomi
Clar, Elana
Azmi, Hooman
Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_full Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_fullStr Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_full_unstemmed Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_short Treatment of Acute Delirium in a Patient with Parkinson’s Disease by Transfer to the Intensive Care Unit and Administration of Dexmedetomidine
title_sort treatment of acute delirium in a patient with parkinson’s disease by transfer to the intensive care unit and administration of dexmedetomidine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280942/
https://www.ncbi.nlm.nih.gov/pubmed/32498499
http://dx.doi.org/10.14802/jmd.20005
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