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Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes

Previous studies have reported age and gender disparities in the occurrence and therapeutic approach of dyslipidemia and (or) coronary heart disease (CHD) in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate these differences in Romanian patients with T2DM. A cross-sectional, ob...

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Autores principales: Găman, Mihnea-Alexandru, Cozma, Matei-Alexandru, Dobrică, Elena-Codruța, Bacalbașa, Nicolae, Bratu, Ovidiu Gabriel, Diaconu, Camelia Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280968/
https://www.ncbi.nlm.nih.gov/pubmed/32423050
http://dx.doi.org/10.3390/metabo10050195
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author Găman, Mihnea-Alexandru
Cozma, Matei-Alexandru
Dobrică, Elena-Codruța
Bacalbașa, Nicolae
Bratu, Ovidiu Gabriel
Diaconu, Camelia Cristina
author_facet Găman, Mihnea-Alexandru
Cozma, Matei-Alexandru
Dobrică, Elena-Codruța
Bacalbașa, Nicolae
Bratu, Ovidiu Gabriel
Diaconu, Camelia Cristina
author_sort Găman, Mihnea-Alexandru
collection PubMed
description Previous studies have reported age and gender disparities in the occurrence and therapeutic approach of dyslipidemia and (or) coronary heart disease (CHD) in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate these differences in Romanian patients with T2DM. A cross-sectional, observational, retrospective study was conducted using the medical records of T2DM patients who attended the outpatient facility of the Internal Medicine Clinic of the Clinical Emergency Hospital of Bucharest, Romania for routine check-ups in a six-month period. We analyzed the records of 217 diabetic patients (mean age 69 ± 11 years; 51.15% women). We found no significant gender differences in the occurrence of dyslipidemia, CHD or CHD + dyslipidemia or in terms of statin prescription. However; patients aged 65 years or older were significantly more affected by dyslipidemia, CHD or CHD + dyslipidemia, versus subjects aged <65 years. Further, they were more likely to be prescribed statin therapy (p < 0.0001 for all). Statins were prescribed to 67.24% of the patients with dyslipidemia; 61.01% of the subjects with CHD; and to 91.48% of the patients who had both conditions. e recorded no gender differences in the occurrence of CHD and (or) dyslipidemia in Romanian T2DM patients. Patients aged 65 years or older had a higher prevalence of CHD and/or dyslipidemia, and were more likely to be prescribed statins, versus younger counterparts. However, many T2DM patients with CHD and (or) dyslipidemia were undertreated: Nearly 33% of the subjects with dyslipidemia, and nearly 40% of the ones with CHD were not prescribed statins.
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spelling pubmed-72809682020-06-15 Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes Găman, Mihnea-Alexandru Cozma, Matei-Alexandru Dobrică, Elena-Codruța Bacalbașa, Nicolae Bratu, Ovidiu Gabriel Diaconu, Camelia Cristina Metabolites Article Previous studies have reported age and gender disparities in the occurrence and therapeutic approach of dyslipidemia and (or) coronary heart disease (CHD) in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate these differences in Romanian patients with T2DM. A cross-sectional, observational, retrospective study was conducted using the medical records of T2DM patients who attended the outpatient facility of the Internal Medicine Clinic of the Clinical Emergency Hospital of Bucharest, Romania for routine check-ups in a six-month period. We analyzed the records of 217 diabetic patients (mean age 69 ± 11 years; 51.15% women). We found no significant gender differences in the occurrence of dyslipidemia, CHD or CHD + dyslipidemia or in terms of statin prescription. However; patients aged 65 years or older were significantly more affected by dyslipidemia, CHD or CHD + dyslipidemia, versus subjects aged <65 years. Further, they were more likely to be prescribed statin therapy (p < 0.0001 for all). Statins were prescribed to 67.24% of the patients with dyslipidemia; 61.01% of the subjects with CHD; and to 91.48% of the patients who had both conditions. e recorded no gender differences in the occurrence of CHD and (or) dyslipidemia in Romanian T2DM patients. Patients aged 65 years or older had a higher prevalence of CHD and/or dyslipidemia, and were more likely to be prescribed statins, versus younger counterparts. However, many T2DM patients with CHD and (or) dyslipidemia were undertreated: Nearly 33% of the subjects with dyslipidemia, and nearly 40% of the ones with CHD were not prescribed statins. MDPI 2020-05-14 /pmc/articles/PMC7280968/ /pubmed/32423050 http://dx.doi.org/10.3390/metabo10050195 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Găman, Mihnea-Alexandru
Cozma, Matei-Alexandru
Dobrică, Elena-Codruța
Bacalbașa, Nicolae
Bratu, Ovidiu Gabriel
Diaconu, Camelia Cristina
Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes
title Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes
title_full Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes
title_fullStr Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes
title_full_unstemmed Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes
title_short Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes
title_sort dyslipidemia: a trigger for coronary heart disease in romanian patients with diabetes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280968/
https://www.ncbi.nlm.nih.gov/pubmed/32423050
http://dx.doi.org/10.3390/metabo10050195
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