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Advances in Histone Demethylase KDM3A as a Cancer Therapeutic Target

Lysine-specific histone demethylase 3 (KDM3) subfamily proteins are H3K9me2/me1 histone demethylases that promote gene expression. The KDM3 subfamily primarily consists of four proteins (KDM3A−D). All four proteins contain the catalytic Jumonji C domain (JmjC) at their C-termini, but whether KDM3C h...

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Detalles Bibliográficos
Autores principales: Yoo, Jung, Jeon, Yu Hyun, Cho, Ha Young, Lee, Sang Wu, Kim, Go Woon, Lee, Dong Hoon, Kwon, So Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280979/
https://www.ncbi.nlm.nih.gov/pubmed/32354028
http://dx.doi.org/10.3390/cancers12051098

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