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High-Throughput Identification of MiR-145 Targets in Human Articular Chondrocytes

MicroRNAs (miRNAs) play key roles in cartilage development and homeostasis and are dysregulated in osteoarthritis. MiR-145 modulation induces profound changes in the human articular chondrocyte (HAC) phenotype, partially through direct repression of SOX9. Since miRNAs can simultaneously silence mult...

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Detalles Bibliográficos
Autores principales:	Martinez-Sanchez, Aida, Lazzarano, Stefano, Sharma, Eshita, Lockstone, Helen, Murphy, Christopher L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281014/ https://www.ncbi.nlm.nih.gov/pubmed/32403239 http://dx.doi.org/10.3390/life10050058

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