Azasteroid Alkylators as Dual Inhibitors of AKT and ERK Signaling for the Treatment of Ovarian Carcinoma

(1) Background: Previous findings show that lactam steroidal alkylating esters display improved therapeutic efficacy with reduced toxicity. The aim of this study was to evaluate the anticancer activity of two newly synthesized aza-steroid alkylators (ENGA-L06E and ENGA-L08E) against human ovarian ca...

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Detalles Bibliográficos
Autores principales: Dalezis, Panagiotis, Geromichalou, Eleni, Polonifi, Aikaterini, Sagredou, Sofia, Nikoleousakos, Nikolaos, Nikolaou, Michael, Sarli, Vasiliki, Panayiotidis, Mihalis I., Trafalis, Dimitrios T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281072/
https://www.ncbi.nlm.nih.gov/pubmed/32429466
http://dx.doi.org/10.3390/cancers12051263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281072/
https://www.ncbi.nlm.nih.gov/pubmed/32429466
http://dx.doi.org/10.3390/cancers12051263

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