Spectrum of Germline BRCA1 and BRCA2 Variants Identified in 2351 Ovarian and Breast Cancer Patients Referring to a Reference Cancer Hospital of Rome

Pathogenic variants (PVs) carriers in BRCA1 or BRCA2 are associated with an elevated lifetime risk of developing breast cancer (BC) and/or ovarian cancer (OC). The prevalence of BRCA1 and BRCA2 germline alterations is extremely variable among different ethnic groups. Particularly, the rate of varian...

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Detalles Bibliográficos
Autores principales: Santonocito, Concetta, Rizza, Roberta, Paris, Ida, De Marchis, Laura, Paolillo, Carmela, Tiberi, Giordana, Scambia, Giovanni, Capoluongo, Ettore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281099/
https://www.ncbi.nlm.nih.gov/pubmed/32438681
http://dx.doi.org/10.3390/cancers12051286

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