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Are Pathogenic Germline Variants in Metastatic Melanoma Associated with Resistance to Combined Immunotherapy?

Background: Combined immunotherapy has significantly improved survival of patients with advanced melanoma, but there are still patients that do not benefit from it. Early biomarkers that indicate potential resistance would be highly relevant for these patients. Methods: We comprehensively analyzed t...

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Detalles Bibliográficos
Autores principales: Amaral, Teresa, Schulze, Martin, Sinnberg, Tobias, Nieser, Maike, Martus, Peter, Battke, Florian, Garbe, Claus, Biskup, Saskia, Forschner, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281129/
https://www.ncbi.nlm.nih.gov/pubmed/32354124
http://dx.doi.org/10.3390/cancers12051101