Higher Responsiveness to Rosuvastatin in Polygenic versus Monogenic Hypercholesterolemia: A Propensity Score Analysis

Background: The monogenic defect in familial hypercholesterolemia (FH) is detected in ∼40% of cases. The majority of mutation-negative patients have a polygenic cause of high LDL-cholesterol (LDL-C). We sought to investigate whether the underlying monogenic or polygenic defect is associated with the...

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Detalles Bibliográficos
Autores principales: Mickiewicz, Agnieszka, Futema, Marta, Ćwiklinska, Agnieszka, Kuchta, Agnieszka, Jankowski, Maciej, Kaszubowski, Mariusz, Chmara, Magdalena, Wasąg, Bartosz, Fijałkowski, Marcin, Jaguszewski, Miłosz, Humphries, Steve E., Gruchała, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281142/
https://www.ncbi.nlm.nih.gov/pubmed/32443900
http://dx.doi.org/10.3390/life10050073

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