Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer

The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred metabolic pathway even in aerobic conditions. Targeting the Warburg effect to specifically deliver sugar conjugated cytotoxic compounds into tumor c...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Pelageev, Dmitry N., Hauschild, Jessica, Sabutskii, Yurii E., Khmelevskaya, Ekaterina A., Krisp, Christoph, Kaune, Moritz, Venz, Simone, Borisova, Ksenia L., Busenbender, Tobias, Denisenko, Vladimir A., Schlüter, Hartmut, Bokemeyer, Carsten, Graefen, Markus, Polonik, Sergey G., Anufriev, Victor Ph., von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281150/
https://www.ncbi.nlm.nih.gov/pubmed/32403427
http://dx.doi.org/10.3390/md18050251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281150/
https://www.ncbi.nlm.nih.gov/pubmed/32403427
http://dx.doi.org/10.3390/md18050251

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