Cargando…

Integrative Analysis of Fecal Metagenomics and Metabolomics in Colorectal Cancer

Although colorectal cancer (CRC) is the second leading cause of death in developed countries, current diagnostic tests for early disease stages are suboptimal. We have performed a combination of UHPLC-MS metabolomics and 16S microbiome analyses on 224 feces samples in order to identify early biomark...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clos-Garcia, Marc, Garcia, Koldo, Alonso, Cristina, Iruarrizaga-Lejarreta, Marta, D’Amato, Mauro, Crespo, Anais, Iglesias, Agueda, Cubiella, Joaquín, Bujanda, Luis, Falcón-Pérez, Juan Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281174/ https://www.ncbi.nlm.nih.gov/pubmed/32370168 http://dx.doi.org/10.3390/cancers12051142

Ejemplares similares

Interplay between Genome, Metabolome and Microbiome in Colorectal Cancer
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2021)

A Comprehensive Metabolomics Analysis of Fecal Samples from Advanced Adenoma and Colorectal Cancer Patients
por: Telleria, Oiana, et al.
Publicado: (2022)

Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer
por: Cubiella, Joaquin, et al.
Publicado: (2018)

Faecal Diagnostic Biomarkers for Colorectal Cancer
por: Cruz, Andrea, et al.
Publicado: (2021)

A Novel Approach on the Use of Samples from Faecal Occult Blood Screening Kits for Metabolomics Analysis: Application in Colorectal Cancer Population
por: Albóniga, Oihane E., et al.
Publicado: (2023)

Utility of Metabolomic Biomarkers to Identify Nonalcoholic Fatty Liver Disease in Liver Transplant Recipients
por: Mowry, Christopher J., et al.
Publicado: (2021)

Performance of the Use of Genetic Information to Assess the Risk of Colorectal Cancer in the Basque Population
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2022)

Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2023)

The effect of starch- and sucrose-reduced diet accompanied by nutritional and culinary recommendations on the symptoms of irritable bowel syndrome patients with diarrhoea
por: Gayoso, Lucia, et al.
Publicado: (2023)

Fecal occult blood and calprotectin testing to prioritize primary care patients for colonoscopy referral: The advantage study
por: Lanas, Ángel, et al.
Publicado: (2023)

Alteration in the Cerebrospinal Fluid Lipidome in Parkinson’s Disease: A Post-Mortem Pilot Study
por: Fernández-Irigoyen, Joaquín, et al.
Publicado: (2021)

A 1 year course of starch- and sucrose-reduced diet used by irritable bowel syndrome patients with diarrhoea and the effect of genetic variants
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2023)

Symptom or faecal immunochemical test based referral criteria for colorectal cancer detection in symptomatic patients: a diagnostic tests study
por: Herrero, Jesús-Miguel, et al.
Publicado: (2018)

Impact of the faecal immunochemical test on colorectal cancer survival
por: Gutierrez-Stampa, María Angeles, et al.
Publicado: (2020)

Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations
por: Sinha, Rashmi, et al.
Publicado: (2016)

Optimal diagnostic accuracy of quantitative faecal immunochemical test positivity thresholds for colorectal cancer detection in primary health care: A community‐based cohort study
por: Pin‐Vieito, Noel, et al.
Publicado: (2021)

Local genetic variation of inflammatory bowel disease in Basque population and its effect in risk prediction
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2022)

Colorectal Cancer Survival in 50- to 69-Year-Olds after Introducing the Faecal Immunochemical Test
por: Gutierrez-Stampa, María Angeles, et al.
Publicado: (2020)

Comparison of Fecal Collection Methods on Variation in Gut Metagenomics and Untargeted Metabolomics
por: Guan, Huihui, et al.
Publicado: (2021)

Consistency of metagenomic assignment programs in simulated and real data
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2014)

Integrated Analysis of the Fecal Metagenome and Metabolome in Bladder Cancer in a Chinese Population
por: Qin, Chuan, et al.
Publicado: (2022)

Metagenomic and metabolomic analyses reveal synergistic effects of fecal microbiota transplantation and anti-PD-1 therapy on treating colorectal cancer
por: Huang, Jiayuan, et al.
Publicado: (2022)

Fecal Metagenomics and Metabolomics Identifying Microbial Signatures in Non-Alcoholic Fatty Liver Disease
por: Pekkala, Satu
Publicado: (2023)

Taxonomic and functional profiling of fecal metagenomes for the early detection of colorectal cancer
por: Wu, Xudong, et al.
Publicado: (2023)

Polyprev: Randomized, Multicenter, Controlled Trial Comparing Fecal Immunochemical Test with Endoscopic Surveillance after Advanced Adenoma Resection in Colorectal Cancer Screening Programs: A Study Protocol
por: Regueiro, Cristina, et al.
Publicado: (2021)

Applicability of polygenic risk scores in endometriosis clinical presentation
por: Svensson, Agnes, et al.
Publicado: (2022)

Meta-Analysis and Validation of a Colorectal Cancer Risk Prediction Model Using Deep Sequenced Fecal Metagenomes
por: Obón-Santacana, Mireia, et al.
Publicado: (2022)

Targeted depletion of pks+ bacteria from a fecal microbiota using specific antibodies
por: Blanco-Míguez, Aitor, et al.
Publicado: (2023)

A New Method for Extracting Skin Microbes Allows Metagenomic Analysis of Whole-Deep Skin
por: Garcia-Garcerà, Marc, et al.
Publicado: (2013)

Risk of Advanced Neoplasia in First-Degree Relatives with Colorectal Cancer: A Large Multicenter Cross-Sectional Study
por: Quintero, Enrique, et al.
Publicado: (2016)

Expanding the taxonomic range in the fecal metagenome
por: Allnutt, Theo R., et al.
Publicado: (2021)

Predictive Value of Carcinoembryonic Antigen in Symptomatic Patients without Colorectal Cancer: A Post-Hoc Analysis within the COLONPREDICT Cohort
por: Pin-Vieito, Noel, et al.
Publicado: (2020)

Host Genetics and Microbiota Interactions in Colorectal Cancer: Shared or Independent Risk?
por: Romero-Garmendia, Irati, et al.
Publicado: (2022)

From Omic Layers to Personalized Medicine in Colorectal Cancer: The Road Ahead
por: Romero-Garmendia, Irati, et al.
Publicado: (2023)

Metagenomic Analysis of the Ferret Fecal Viral Flora
por: Smits, Saskia L., et al.
Publicado: (2013)

Towards diagnostic metagenomics of Campylobacter in fecal samples
por: Andersen, Sandra Christine, et al.
Publicado: (2017)

Metagenomic Analysis of the Jinding Duck Fecal Virome
por: Zhao, Lili, et al.
Publicado: (2018)

Metagenomic analysis of the fecal microbiome in colorectal cancer patients compared to healthy controls as a function of age
por: Kharofa, Jordan, et al.
Publicado: (2022)

NMR-based fecal metabolomics fingerprinting as predictors of earlier diagnosis in patients with colorectal cancer
por: Lin, Yan, et al.
Publicado: (2016)

Alterations of the Gut Microbiome and Fecal Metabolome in Colorectal Cancer: Implication of Intestinal Metabolism for Tumorigenesis
por: Du, Xinhao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sradf0176l2khmplcc17tt2lsu