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Advantages of Using Paclitaxel in Combination with Oncolytic Adenovirus Utilizing RNA Destabilization Mechanism

Oncolytic virotherapy is a novel approach to cancer therapy. Ad-fosARE is a conditionally replicative adenovirus engineered by inserting AU-rich elements (ARE) in the 3’-untranslated region of the E1A gene. In this study, we examined the oncolytic activity of Ad-fosARE and used it in a synergistic c...

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Detalles Bibliográficos
Autores principales: Hossain, Elora, Habiba, Umma, Yanagawa-Matsuda, Aya, Alam, Arefin, Ahmed, Ishraque, Towfik Alam, Mohammad, Yasuda, Motoaki, Higashino, Fumihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281177/
https://www.ncbi.nlm.nih.gov/pubmed/32408515
http://dx.doi.org/10.3390/cancers12051210

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