Cargando…
Targeting Protein Synthesis in Colorectal Cancer
Under physiological conditions, protein synthesis controls cell growth and survival and is strictly regulated. Deregulation of protein synthesis is a frequent event in cancer. The majority of mutations found in colorectal cancer (CRC), including alterations in the WNT pathway as well as activation o...
Autores principales: | Schmidt, Stefanie, Denk, Sarah, Wiegering, Armin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281195/ https://www.ncbi.nlm.nih.gov/pubmed/32455578 http://dx.doi.org/10.3390/cancers12051298 |
Ejemplares similares
-
Targeting bromodomain-containing protein 4 (BRD4) inhibits MYC expression in colorectal cancer cells
por: Otto, C., et al.
Publicado: (2019) -
CIP2A regulates MYC translation (via its 5′UTR) in colorectal cancer
por: Denk, S., et al.
Publicado: (2020) -
RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells
por: Otto, Christoph, et al.
Publicado: (2022) -
Organoid Models for Cancer Research—From Bed to Bench Side and Back
por: Kastner, Carolin, et al.
Publicado: (2021) -
A MYC/GCN2/eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer
por: Schmidt, Stefanie, et al.
Publicado: (2019)