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Knockout of MMP3 Weakens Solid Tumor Organoids and Cancer Extracellular Vesicles

The tumor organoid (tumoroid) model in three-dimensional (3D) culture systems has been developed to reflect more closely the in vivo tumors than 2D-cultured tumor cells. Notably, extracellular vesicles (EVs) are efficiently collectible from the culture supernatant of gel-free tumoroids. Matrix metal...

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Detalles Bibliográficos
Autores principales: Taha, Eman A., Sogawa, Chiharu, Okusha, Yuka, Kawai, Hotaka, Oo, May Wathone, Elseoudi, Abdellatif, Lu, Yanyin, Nagatsuka, Hitoshi, Kubota, Satoshi, Satoh, Ayano, Okamoto, Kuniaki, Eguchi, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281240/
https://www.ncbi.nlm.nih.gov/pubmed/32429403
http://dx.doi.org/10.3390/cancers12051260