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Venous Thromboembolism in Cancer Patients on Simultaneous and Palliative Care
Simultaneous care represents the ideal integration between early supportive and palliative care in cancer patients under active antineoplastic treatment. Cancer patients require a composite clinical, social and psychological management that can be effective only if care continuity from hospital to h...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281278/ https://www.ncbi.nlm.nih.gov/pubmed/32384641 http://dx.doi.org/10.3390/cancers12051167 |
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author | Riondino, Silvia Ferroni, Patrizia Del Monte, Girolamo Formica, Vincenzo Guadagni, Fiorella Roselli, Mario |
author_facet | Riondino, Silvia Ferroni, Patrizia Del Monte, Girolamo Formica, Vincenzo Guadagni, Fiorella Roselli, Mario |
author_sort | Riondino, Silvia |
collection | PubMed |
description | Simultaneous care represents the ideal integration between early supportive and palliative care in cancer patients under active antineoplastic treatment. Cancer patients require a composite clinical, social and psychological management that can be effective only if care continuity from hospital to home is guaranteed and if such a care takes place early in the course of the disease, combining standard oncology care and palliative care. In these settings, venous thromboembolism (VTE) represents a difficult medical challenge, for the requirement of acute treatments and for the strong impact on anticancer therapies that might be delayed or, even, totally discontinued. Moreover, cancer patients not only display high rates of VTE occurrence/recurrence but are also more prone to bleeding and this forces clinicians to optimize treatment strategies, balancing between hemorrhages and thrombus formation. VTE prevention is, therefore, regarded as a double-edged sword. Indeed, while on one hand the appropriate use of antithrombotic agents can reduce VTE occurrence, on the other it significantly increases the bleeding risk, especially in the frail patients who present with multiple co-morbidities and poly-therapy that can interact with anticoagulant drugs. For these reasons, thromboprophylaxis should start while active cancer treatment is ongoing, according to a simultaneous care model in a patient-centered perspective. |
format | Online Article Text |
id | pubmed-7281278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72812782020-06-19 Venous Thromboembolism in Cancer Patients on Simultaneous and Palliative Care Riondino, Silvia Ferroni, Patrizia Del Monte, Girolamo Formica, Vincenzo Guadagni, Fiorella Roselli, Mario Cancers (Basel) Review Simultaneous care represents the ideal integration between early supportive and palliative care in cancer patients under active antineoplastic treatment. Cancer patients require a composite clinical, social and psychological management that can be effective only if care continuity from hospital to home is guaranteed and if such a care takes place early in the course of the disease, combining standard oncology care and palliative care. In these settings, venous thromboembolism (VTE) represents a difficult medical challenge, for the requirement of acute treatments and for the strong impact on anticancer therapies that might be delayed or, even, totally discontinued. Moreover, cancer patients not only display high rates of VTE occurrence/recurrence but are also more prone to bleeding and this forces clinicians to optimize treatment strategies, balancing between hemorrhages and thrombus formation. VTE prevention is, therefore, regarded as a double-edged sword. Indeed, while on one hand the appropriate use of antithrombotic agents can reduce VTE occurrence, on the other it significantly increases the bleeding risk, especially in the frail patients who present with multiple co-morbidities and poly-therapy that can interact with anticoagulant drugs. For these reasons, thromboprophylaxis should start while active cancer treatment is ongoing, according to a simultaneous care model in a patient-centered perspective. MDPI 2020-05-06 /pmc/articles/PMC7281278/ /pubmed/32384641 http://dx.doi.org/10.3390/cancers12051167 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Riondino, Silvia Ferroni, Patrizia Del Monte, Girolamo Formica, Vincenzo Guadagni, Fiorella Roselli, Mario Venous Thromboembolism in Cancer Patients on Simultaneous and Palliative Care |
title | Venous Thromboembolism in Cancer Patients on Simultaneous and Palliative Care |
title_full | Venous Thromboembolism in Cancer Patients on Simultaneous and Palliative Care |
title_fullStr | Venous Thromboembolism in Cancer Patients on Simultaneous and Palliative Care |
title_full_unstemmed | Venous Thromboembolism in Cancer Patients on Simultaneous and Palliative Care |
title_short | Venous Thromboembolism in Cancer Patients on Simultaneous and Palliative Care |
title_sort | venous thromboembolism in cancer patients on simultaneous and palliative care |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281278/ https://www.ncbi.nlm.nih.gov/pubmed/32384641 http://dx.doi.org/10.3390/cancers12051167 |
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