PLZF-RAR(α), NPM1-RAR(α), and Other Acute Promyelocytic Leukemia Variants: The PETHEMA Registry Experience and Systematic Literature Review

It has been suggested that 1–2% of acute promyelocytic leukemia (APL) patients present variant rearrangements of retinoic acid receptor alpha (RARα) fusion gene, with the promyelocytic leukaemia zinc finger (PLZF)/RAR(α) being the most frequent. Resistance to all-trans-retinoic acid (ATRA) and arsen...

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Detalles Bibliográficos
Autores principales: Sobas, Marta, Talarn-Forcadell, Maria Carme, Martínez-Cuadrón, David, Escoda, Lourdes, García-Pérez, María J., Mariz, Jose, Mela-Osorio, María J., Fernández, Isolda, Alonso-Domínguez, Juan M., Cornago-Navascués, Javier, Rodríguez-Macias, Gabriela, Amutio, María E., Rodríguez-Medina, Carlos, Esteve, Jordi, Sokół, Agnieszka, Murciano-Carrillo, Thais, Calasanz, María J., Barrios, Manuel, Barragán, Eva, Sanz, Miguel A., Montesinos, Pau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281281/
https://www.ncbi.nlm.nih.gov/pubmed/32455804
http://dx.doi.org/10.3390/cancers12051313

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