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HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth

In addition to genetic changes, post-transcriptional events strongly contribute to the progression of malignant tumors. The RNA-binding protein HuR (ELAVL1) is able to bind and stabilize a large group of target mRNAs, which contain AU-rich elements (ARE) in their 3′-untranslated region. We found HuR...

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Detalles Bibliográficos
Autores principales:	Liebig, Janika K., Kuphal, Silke, Bosserhoff, Anja Katrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281285/ https://www.ncbi.nlm.nih.gov/pubmed/32455577 http://dx.doi.org/10.3390/cancers12051299

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