Neospora caninum: Structure and Fate of Multinucleated Complexes Induced by the Bumped Kinase Inhibitor BKI-1294

Background: Bumped kinase inhibitors (BKIs) are potential drugs for neosporosis treatment in farm animals. BKI-1294 exposure results in the formation of multinucleated complexes (MNCs), which remain viable in vitro under constant drug pressure. We investigated the formation of BKI-1294 induced MNCs,...

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Detalles Bibliográficos
Autores principales: Winzer, Pablo, Anghel, Nicoleta, Imhof, Dennis, Balmer, Vreni, Ortega-Mora, Luis-Miguel, Ojo, Kayode K., Van Voorhis, Wesley C., Müller, Joachim, Hemphill, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281336/
https://www.ncbi.nlm.nih.gov/pubmed/32429314
http://dx.doi.org/10.3390/pathogens9050382

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