Cargando…

Phenotypic Heterogeneity and Plasticity of Cancer Cell Migration in a Pancreatic Tumor Three-Dimensional Culture Model

Invasive cancer cell migration is a key feature of metastatic human pancreatic ductal adenocarcinoma (PDAC), yet the underlying mechanisms remain poorly understood. Here, we investigated modes of cancer cell invasion using two pancreatic cancer cell lines with differential epithelial–mesenchymal sta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Seul-Ki, Jang, So Dam, Kim, Hyunho, Chung, Seok, Park, Jong Kook, Kuh, Hyo-Jeong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281339/ https://www.ncbi.nlm.nih.gov/pubmed/32455681 http://dx.doi.org/10.3390/cancers12051305

Ejemplares similares

Anti-Cancer Activity Profiling of Chemotherapeutic Agents in 3D Co-Cultures of Pancreatic Tumor Spheroids with Cancer-Associated Fibroblasts and Macrophages
por: Jang, So-Dam, et al.
Publicado: (2021)

Three-Dimensional Imaging for Multiplex Phenotypic Analysis of Pancreatic Microtumors Grown on a Minipillar Array Chip
por: Oh, Min-Suk, et al.
Publicado: (2020)

Microfluidic co-culture of pancreatic tumor spheroids with stellate cells as a novel 3D model for investigation of stroma-mediated cell motility and drug resistance
por: Lee, Ji-Hyun, et al.
Publicado: (2018)

Three Dimensional Mixed-Cell Spheroids Mimic Stroma-Mediated Chemoresistance and Invasive Migration in hepatocellular carcinoma
por: Khawar, Iftikhar Ali, et al.
Publicado: (2018)

Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model
por: Kim, Hyun-Ah, et al.
Publicado: (2023)

Extracellular Vesicles (EVs) and Pancreatic Cancer: From the Role of EVs to the Interference with EV-Mediated Reciprocal Communication
por: Moeng, Sokviseth, et al.
Publicado: (2020)

The genetics of phenotypic plasticity. XII. Temporal and spatial heterogeneity
por: Scheiner, Samuel M
Publicado: (2013)

Endoscopic management of duodenal perforations caused by migrated biliary plastic stents
por: Kim, Shin Hee, et al.
Publicado: (2019)

Editorial: The heterogeneity in COPD phenotypes
por: Tanabe, Naoya, et al.
Publicado: (2022)

A Model-System to Address the Impact of Phenotypic Heterogeneity and Plasticity on the Development of Cancer Therapies
por: Jong, Eric D., et al.
Publicado: (2019)

Wire-Guided Endoscopic Snare Retrieval of Proximally Migrated Pancreatic Stents after Endoscopic Papillectomy for Ampullary Adenoma
por: Yoon, La Young, et al.
Publicado: (2011)

Microfluidic model for in vitro acute Toxoplasma gondii infection and transendothelial migration
por: Kim, Hyunho, et al.
Publicado: (2022)

Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments
por: Talkenberger, Katrin, et al.
Publicado: (2017)

Cell Heterogeneity and Phenotypic Plasticity in Metastasis Formation: The Case of Colon Cancer
por: Teeuwssen, Miriam, et al.
Publicado: (2019)

Synthesis, Characterization and Properties of Biodegradable Poly(Butylene Sebacate-Co-terephthalate)
por: Kim, Sun Jong, et al.
Publicado: (2020)

Characterization of PLA/PBSeT Blends Prepared with Various Hexamethylene Diisocyanate Contents
por: Kim, Sun Jong, et al.
Publicado: (2021)

Heterogeneity and plasticity of epidermal stem cells
por: Schepeler, Troels, et al.
Publicado: (2014)

Clinical Application of Three-Dimensional Printing Technology in Craniofacial Plastic Surgery
por: Choi, Jong Woo, et al.
Publicado: (2015)

Comparison of the Oocyte Quality Derived from Two-Dimensional Follicle Culture Methods and Developmental Competence of In Vitro Grown and Matured Oocytes
por: Lee, Jaewang, et al.
Publicado: (2018)

Endoscopic retrieval of two proximally migrated plastic pancreatic duct stents
por: Rana, Surinder S, et al.
Publicado: (2019)

Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity
por: Strauss, Robert, et al.
Publicado: (2011)

Evolution from genetics to phenotype: reinterpretation of NSCLC plasticity, heterogeneity, and drug resistance
por: Xue, Yingjiao, et al.
Publicado: (2016)

Exploring Notch Pathway to Elucidate Phenotypic Plasticity and Intra-tumor Heterogeneity in Gliomas
por: Chowdhury, Saikat, et al.
Publicado: (2019)

Phenotypic Heterogeneity of Triple-Negative Breast Cancer Mediated by Epithelial–Mesenchymal Plasticity
por: Kvokačková, Barbora, et al.
Publicado: (2021)

Phenotypic Plasticity Strategy of Aeluropus lagopoides Grass in Response to Heterogenous Saline Habitats
por: Assaeed, Abdulaziz M., et al.
Publicado: (2023)

Erratum: Clinical Application of Three-Dimensional Printing Technology in Craniofacial Plastic Surgery
por: Choi, Jong Woo, et al.
Publicado: (2015)

Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion
por: Cho, Kyung-Ok, et al.
Publicado: (2017)

Corrigendum to: Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion
por: Cho, Kyung-Ok, et al.
Publicado: (2022)

Cellular heterogeneity and plasticity during NAFLD progression
por: Park, Hyun-Ju, et al.
Publicado: (2023)

Antifibrotic effects of pentoxifylline improve the efficacy of gemcitabine in human pancreatic tumor xenografts
por: Kim, Jung Ho, et al.
Publicado: (2017)

Low-Dose Three-Dimensional Rotational Angiography for Evaluating Intracranial Aneurysms: Analysis of Image Quality and Radiation Dose
por: Ki, Hee Jong, et al.
Publicado: (2022)

Correction: Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity
por: Strauss, Robert, et al.
Publicado: (2011)

Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance
por: Ahmed, Farzana, et al.
Publicado: (2018)

Systems-level network modeling deciphers the master regulators of phenotypic plasticity and heterogeneity in melanoma
por: Pillai, Maalavika, et al.
Publicado: (2021)

A Bayesian Approach to Predict Football Matches with Changed Home Advantage in Spectator-Free Matches after the COVID-19 Break
por: Lee, Jaemin, et al.
Publicado: (2022)

A Mathematical Model of Collective Cell Migration in a Three-Dimensional, Heterogeneous Environment
por: Stonko, David P., et al.
Publicado: (2015)

Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype
por: Liffers, Sven-Thorsten, et al.
Publicado: (2023)

Periodontal healing using a collagen matrix with periodontal ligament progenitor cells in a dehiscence defect model in beagle dogs
por: Yoo, Seung-Yoon, et al.
Publicado: (2019)

Diagnostic value of three-dimensional neuroretinal rim thickness for differentiation of superior segmental optic nerve hypoplasia
por: Choe, Sooyeon, et al.
Publicado: (2023)

Ecological Risk Assessment of Chemicals Migrated from a Recycled Plastic Product
por: Roh, Ji-Yeon, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_gkqkddq2tto1sacjrlski0hqjm