Breast Fibroblasts and ECM Components Modulate Breast Cancer Cell Migration through the Secretion of MMPs in a 3D Microfluidic Co-Culture Model

The extracellular matrix (ECM) composition greatly influences cancer progression, leading to differential invasion, migration, and metastatic potential. In breast cancer, ECM components, such as fibroblasts and ECM proteins, have the potential to alter cancer cell migration. However, the lack of in...

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Detalles Bibliográficos
Autores principales: Lugo-Cintrón, Karina M., Gong, Max M., Ayuso, José M., Tomko, Lucas A., Beebe, David J., Virumbrales-Muñoz, María, Ponik, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281408/
https://www.ncbi.nlm.nih.gov/pubmed/32384738
http://dx.doi.org/10.3390/cancers12051173

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