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Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression

The 3-hydroxy-3-methylglutaryl-CoA synthase 1 (HMGCS1) is a potential regulatory node in the mevalonate pathway that is frequently dysregulated in tumors. This study found that HMGCS1 expression is upregulated in stomach adenocarcinoma samples of patients and tumorspheres of gastric cancer cells. HM...

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Detalles Bibliográficos
Autores principales:	Wang, I-Han, Huang, Tzu-Ting, Chen, Ji-Lin, Chu, Li-Wei, Ping, Yueh-Hsin, Hsu, Kai-Wen, Huang, Kuo-Hung, Fang, Wen-Liang, Lee, Hsin-Chen, Chen, Chian-Feng, Liao, Chen-Chung, Hsieh, Rong-Hong, Yeh, Tien-Shun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281414/ https://www.ncbi.nlm.nih.gov/pubmed/32349352 http://dx.doi.org/10.3390/cancers12051088

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