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Regulation of Src Family Kinases during Colorectal Cancer Development and Its Clinical Implications
Src family kinases (SFKs) are non-receptor kinases that play a critical role in the pathogenesis of colorectal cancer (CRC). The expression and activity of SFKs are upregulated in patients with CRC. Activation of SFKs promotes CRC cell proliferation, metastases to other organs and chemoresistance, a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281431/ https://www.ncbi.nlm.nih.gov/pubmed/32456226 http://dx.doi.org/10.3390/cancers12051339 |