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Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen

Background: Breast cancer (BC) is a heterogeneous disease for which the commonly used chemotherapeutic agents primarily include the anthracyclines (doxorubicin, epirubicin), microtubule inhibitors (paclitaxel, docetaxel, eribulin), and alkylating agents (cyclophosphamide). While these drugs can be h...

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Detalles Bibliográficos
Autores principales: Bhatia, Sugandha, Blick, Tony, Pinto, Cletus, Waltham, Mark, Monkman, James, Ivanova, Ekaterina, Pollock, Pamela M., Nagaraj, Shivashankar H., Wiegmans, Adrian P., Haviv, Izhak, Simpson, Kaylene J., Thompson, Erik W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281530/
https://www.ncbi.nlm.nih.gov/pubmed/32365878
http://dx.doi.org/10.3390/cancers12051123