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Phylogenetic reconstruction of breast cancer reveals two routes of metastatic dissemination associated with distinct clinical outcome
BACKGROUND: In breast cancer (BC), axillary lymph node (ALN) involvement is one of the strongest adverse prognostic factors. However, it is unclear whether loco-regional lymph node deposits are effectively the root of secondary metastases or only an indicator of competence of the primary tumour to s...
Autores principales: | Venet, David, Fimereli, Danai, Rothé, Françoise, Boeckx, Bram, Maetens, Marion, Majjaj, Samira, Rouas, Ghizlane, Capra, Maria, Bonizzi, Giuseppina, Contaldo, Federica, Galant, Christine, Piccart, Martine, Pruneri, Giancarlo, Larsimont, Denis, Lambrechts, Diether, Desmedt, Christine, Sotiriou, Christos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281848/ https://www.ncbi.nlm.nih.gov/pubmed/32512508 http://dx.doi.org/10.1016/j.ebiom.2020.102793 |
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