Cargando…
Midfoot Arthritis in Children: Is There Any Relation With Malignancy?
BACKGROUND: Musculoskeletal symptoms are a presenting manifestation in a number of lymphoproliferative disorders including leukemia, especially in children. Among these primary symptoms, midfoot arthritis seems to be an important alarm for malignancy in children. The aim of this study is evaluation...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281876/ https://www.ncbi.nlm.nih.gov/pubmed/32550767 http://dx.doi.org/10.1177/1179544120924643 |
_version_ | 1783544016340516864 |
---|---|
author | Shiari, Reza Salar, Nargess Parvneh, Vadood Javadi Rahmani, Khosro Yeganeh, Mehrnoush Hassas Shiari, Sara |
author_facet | Shiari, Reza Salar, Nargess Parvneh, Vadood Javadi Rahmani, Khosro Yeganeh, Mehrnoush Hassas Shiari, Sara |
author_sort | Shiari, Reza |
collection | PubMed |
description | BACKGROUND: Musculoskeletal symptoms are a presenting manifestation in a number of lymphoproliferative disorders including leukemia, especially in children. Among these primary symptoms, midfoot arthritis seems to be an important alarm for malignancy in children. The aim of this study is evaluation association of midfoot arthritis with malignancy in children. METHOD: In this cross-sectional study, all medical records of patients with arthritis were identified and reviewed. All clinical and laboratory data were recorded in the information form and data were analyzed by SPSS 25 software. RESULTS: A total of 557 cases of arthritis were evaluated, of which 18 (3.2%) cases have primary symptoms of midfoot arthritis. Four of 18 patients (22.2%) had B-cell precursor acute lymphoblastic leukemia, that midfoot arthritis was their first manifestation. Also, their laboratory findings confirmed that platelet, lactic acid dehydrogenesis, and uric acid values were significantly higher in these children. Based on statistical evaluation, there was no significant difference between age and sex in these patients. CONCLUSION: According to the findings of the present study, it can be concluded that “midfoot arthritis” may be the first manifestation of leukemia in children even with a near-normal hematologic values. |
format | Online Article Text |
id | pubmed-7281876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-72818762020-06-17 Midfoot Arthritis in Children: Is There Any Relation With Malignancy? Shiari, Reza Salar, Nargess Parvneh, Vadood Javadi Rahmani, Khosro Yeganeh, Mehrnoush Hassas Shiari, Sara Clin Med Insights Arthritis Musculoskelet Disord Original Research BACKGROUND: Musculoskeletal symptoms are a presenting manifestation in a number of lymphoproliferative disorders including leukemia, especially in children. Among these primary symptoms, midfoot arthritis seems to be an important alarm for malignancy in children. The aim of this study is evaluation association of midfoot arthritis with malignancy in children. METHOD: In this cross-sectional study, all medical records of patients with arthritis were identified and reviewed. All clinical and laboratory data were recorded in the information form and data were analyzed by SPSS 25 software. RESULTS: A total of 557 cases of arthritis were evaluated, of which 18 (3.2%) cases have primary symptoms of midfoot arthritis. Four of 18 patients (22.2%) had B-cell precursor acute lymphoblastic leukemia, that midfoot arthritis was their first manifestation. Also, their laboratory findings confirmed that platelet, lactic acid dehydrogenesis, and uric acid values were significantly higher in these children. Based on statistical evaluation, there was no significant difference between age and sex in these patients. CONCLUSION: According to the findings of the present study, it can be concluded that “midfoot arthritis” may be the first manifestation of leukemia in children even with a near-normal hematologic values. SAGE Publications 2020-06-08 /pmc/articles/PMC7281876/ /pubmed/32550767 http://dx.doi.org/10.1177/1179544120924643 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Shiari, Reza Salar, Nargess Parvneh, Vadood Javadi Rahmani, Khosro Yeganeh, Mehrnoush Hassas Shiari, Sara Midfoot Arthritis in Children: Is There Any Relation With Malignancy? |
title | Midfoot Arthritis in Children: Is There Any Relation With
Malignancy? |
title_full | Midfoot Arthritis in Children: Is There Any Relation With
Malignancy? |
title_fullStr | Midfoot Arthritis in Children: Is There Any Relation With
Malignancy? |
title_full_unstemmed | Midfoot Arthritis in Children: Is There Any Relation With
Malignancy? |
title_short | Midfoot Arthritis in Children: Is There Any Relation With
Malignancy? |
title_sort | midfoot arthritis in children: is there any relation with
malignancy? |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281876/ https://www.ncbi.nlm.nih.gov/pubmed/32550767 http://dx.doi.org/10.1177/1179544120924643 |
work_keys_str_mv | AT shiarireza midfootarthritisinchildrenisthereanyrelationwithmalignancy AT salarnargess midfootarthritisinchildrenisthereanyrelationwithmalignancy AT parvnehvadoodjavadi midfootarthritisinchildrenisthereanyrelationwithmalignancy AT rahmanikhosro midfootarthritisinchildrenisthereanyrelationwithmalignancy AT yeganehmehrnoushhassas midfootarthritisinchildrenisthereanyrelationwithmalignancy AT shiarisara midfootarthritisinchildrenisthereanyrelationwithmalignancy |