Co-delivery of miR-29b and germacrone based on cyclic RGD-modified nanoparticles for liver fibrosis therapy

Hepatic stellate cells (HSCs) were activated and secreted excessive amounts of extracellular matrix (ECM) proteins during pathogenetic progress of liver fibrosis. Germacrone (GMO) and miR-29b can play an important role in inhibiting growth of HSCs and production of type I collagen. GMO and miR-29b w...

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Detalles Bibliográficos
Autores principales: Ji, De, Wang, Qiaohan, Zhao, Qi, Tong, Huangjin, Yu, Mengting, Wang, Meng, Lu, Tulin, Jiang, Chengxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281922/
https://www.ncbi.nlm.nih.gov/pubmed/32513194
http://dx.doi.org/10.1186/s12951-020-00645-y

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