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Rosuvastatin protects against endothelial cell apoptosis in vitro and alleviates atherosclerosis in ApoE(-/-) mice by suppressing endoplasmic reticulum stress
The development of abnormal lipid-induced atherosclerosis is initiated with endothelial cell apoptosis. Vascular endothelial cells possess highly developed endoplasmic reticulum (ER), which is involved in lipid metabolism, indicating that ER stress may contribute chiefly to the induction of endothel...
Autores principales: | Geng, Jianan, Xu, Huali, Fu, Wenwen, Yu, Xiaofeng, Xu, Guoliang, Cao, Hongyan, Lin, Guangzhu, Sui, Dayun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282009/ https://www.ncbi.nlm.nih.gov/pubmed/32537013 http://dx.doi.org/10.3892/etm.2020.8733 |
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