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Estimating breast tissue-specific DNA methylation age using next-generation sequencing data
BACKGROUND: DNA methylation (DNAm) age has been widely accepted as an epigenetic biomarker for biological aging. Emerging evidence suggests that DNAm age can be tissue-specific and female breast tissue ages faster than other parts of the body. The Horvath clock, which estimates DNAm age across multi...
Autores principales: | Castle, James R., Lin, Nan, Liu, Jinpeng, Storniolo, Anna Maria V., Shendre, Aditi, Hou, Lifang, Horvath, Steve, Liu, Yunlong, Wang, Chi, He, Chunyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282053/ https://www.ncbi.nlm.nih.gov/pubmed/32164769 http://dx.doi.org/10.1186/s13148-020-00834-4 |
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