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Estimating breast tissue-specific DNA methylation age using next-generation sequencing data

BACKGROUND: DNA methylation (DNAm) age has been widely accepted as an epigenetic biomarker for biological aging. Emerging evidence suggests that DNAm age can be tissue-specific and female breast tissue ages faster than other parts of the body. The Horvath clock, which estimates DNAm age across multi...

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Detalles Bibliográficos
Autores principales: Castle, James R., Lin, Nan, Liu, Jinpeng, Storniolo, Anna Maria V., Shendre, Aditi, Hou, Lifang, Horvath, Steve, Liu, Yunlong, Wang, Chi, He, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282053/
https://www.ncbi.nlm.nih.gov/pubmed/32164769
http://dx.doi.org/10.1186/s13148-020-00834-4

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