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Downregulation of DEC1 by RNA interference attenuates ischemia/reperfusion-induced myocardial inflammation by inhibiting the TLR4/NF-κB signaling pathway

Inflammation has been implicated in the pathogenesis of myocardial ischemia/reperfusion (I/R) injury (MIRI). Previous studies have confirmed that deleted in esophageal cancer 1 (DEC1) is an important transcription factor in inflammation. However, the role of DEC1 in MIRI remains unclear. The present...

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Detalles Bibliográficos
Autores principales:	Xu, Weipan, Zhang, Kai, Zhang, Yi, Ma, Shanxue, Jin, Daoqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282085/ https://www.ncbi.nlm.nih.gov/pubmed/32537000 http://dx.doi.org/10.3892/etm.2020.8706

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