Clinical application of the AUC-guided dosage adjustment of docetaxel-based chemotherapy for patients with solid tumours: a single centre, prospective and randomised control study

BACKGROUND: Docetaxel (DTX) is a widely used anti-tumour drug, and its dosage is solely determined by body surface area (BSA). Adverse events, such as neutropenia or unsatisfied efficacy, likely occur because of differences in the pharmacokinetics (PK) and pharmacodynamics of patients. Thus, a feasi...

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Detalles Bibliográficos
Autores principales: Sun, Ning, Shen, Bo, Zhu, Jiali, Zhang, Xiaomei, Zhu, Huayun, Liang, Geyu, Yang, Deliang, Lu, Jianwei, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282138/
https://www.ncbi.nlm.nih.gov/pubmed/32513288
http://dx.doi.org/10.1186/s12967-020-02394-w

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