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Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital

With the continuous spreading of SARS-CoV-2 and increasing number of deaths worldwide, the need and appropriateness for autopsy in patients with COVID-19 became a matter of discussion. In fact, in the COVID-19 era protection of healthcare workers is a priority besides patient management. No evidence...

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Autores principales: Basso, Cristina, Calabrese, Fiorella, Sbaraglia, Marta, Del Vecchio, Claudia, Carretta, Giovanni, Saieva, Annamaria, Donato, Daniele, Flor, Luciano, Crisanti, Andrea, Dei Tos, Angelo Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282199/
https://www.ncbi.nlm.nih.gov/pubmed/32519035
http://dx.doi.org/10.1007/s00428-020-02861-1
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author Basso, Cristina
Calabrese, Fiorella
Sbaraglia, Marta
Del Vecchio, Claudia
Carretta, Giovanni
Saieva, Annamaria
Donato, Daniele
Flor, Luciano
Crisanti, Andrea
Dei Tos, Angelo Paolo
author_facet Basso, Cristina
Calabrese, Fiorella
Sbaraglia, Marta
Del Vecchio, Claudia
Carretta, Giovanni
Saieva, Annamaria
Donato, Daniele
Flor, Luciano
Crisanti, Andrea
Dei Tos, Angelo Paolo
author_sort Basso, Cristina
collection PubMed
description With the continuous spreading of SARS-CoV-2 and increasing number of deaths worldwide, the need and appropriateness for autopsy in patients with COVID-19 became a matter of discussion. In fact, in the COVID-19 era protection of healthcare workers is a priority besides patient management. No evidence is currently available about the real risk related to the procedure as well as to the subsequent management of the samples. We herein describe the procedure that has been used to perform the first series of postmortem examinations in the COVID center of the Padua University Hospital, Padua, Italy, after the implementation of an ad hoc operating procedure, to minimize the risk of infection for pathologists and technicians. Provided that the procedure is performed in an adequate environment respecting strict biosafety rules, our data indicate that complete postmortem examination appears to be safe and will be highly informative providing useful insights into the complex disease pathogenesis.
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spelling pubmed-72821992020-06-09 Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital Basso, Cristina Calabrese, Fiorella Sbaraglia, Marta Del Vecchio, Claudia Carretta, Giovanni Saieva, Annamaria Donato, Daniele Flor, Luciano Crisanti, Andrea Dei Tos, Angelo Paolo Virchows Arch Original Article With the continuous spreading of SARS-CoV-2 and increasing number of deaths worldwide, the need and appropriateness for autopsy in patients with COVID-19 became a matter of discussion. In fact, in the COVID-19 era protection of healthcare workers is a priority besides patient management. No evidence is currently available about the real risk related to the procedure as well as to the subsequent management of the samples. We herein describe the procedure that has been used to perform the first series of postmortem examinations in the COVID center of the Padua University Hospital, Padua, Italy, after the implementation of an ad hoc operating procedure, to minimize the risk of infection for pathologists and technicians. Provided that the procedure is performed in an adequate environment respecting strict biosafety rules, our data indicate that complete postmortem examination appears to be safe and will be highly informative providing useful insights into the complex disease pathogenesis. Springer Berlin Heidelberg 2020-06-09 2020 /pmc/articles/PMC7282199/ /pubmed/32519035 http://dx.doi.org/10.1007/s00428-020-02861-1 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Basso, Cristina
Calabrese, Fiorella
Sbaraglia, Marta
Del Vecchio, Claudia
Carretta, Giovanni
Saieva, Annamaria
Donato, Daniele
Flor, Luciano
Crisanti, Andrea
Dei Tos, Angelo Paolo
Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital
title Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital
title_full Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital
title_fullStr Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital
title_full_unstemmed Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital
title_short Feasibility of postmortem examination in the era of COVID-19 pandemic: the experience of a Northeast Italy University Hospital
title_sort feasibility of postmortem examination in the era of covid-19 pandemic: the experience of a northeast italy university hospital
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282199/
https://www.ncbi.nlm.nih.gov/pubmed/32519035
http://dx.doi.org/10.1007/s00428-020-02861-1
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