Cargando…
The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth
Many proteins have the potential to aggregate into amyloid fibrils, protein polymers associated with a wide range of human disorders such as Alzheimer’s and Parkinson’s disease. The thermodynamic stability of amyloid fibrils, in contrast to that of folded proteins, is not well understood: the balanc...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282669/ https://www.ncbi.nlm.nih.gov/pubmed/32365068 http://dx.doi.org/10.1371/journal.pcbi.1007767 |