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Potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: A rare case report

Peribulbar lignocaine anesthesia is commonly used in ophthalmic surgeries. It rarely causes any severe allergic reaction. A 63-year-old male presented with complicated pseudophakia. He underwent successful vitrectomy under local anesthesia. He later presented with acute-onset proptosis, orbital swel...

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Autores principales: Deshmukh, Saurabh, Bhattacharjee, Harsha, Gupta, Krati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282685/
https://www.ncbi.nlm.nih.gov/pubmed/32565602
http://dx.doi.org/10.4103/ijp.IJP_4_19
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author Deshmukh, Saurabh
Bhattacharjee, Harsha
Gupta, Krati
author_facet Deshmukh, Saurabh
Bhattacharjee, Harsha
Gupta, Krati
author_sort Deshmukh, Saurabh
collection PubMed
description Peribulbar lignocaine anesthesia is commonly used in ophthalmic surgeries. It rarely causes any severe allergic reaction. A 63-year-old male presented with complicated pseudophakia. He underwent successful vitrectomy under local anesthesia. He later presented with acute-onset proptosis, orbital swelling, and extraocular movement restriction. He was afebrile with normal blood workup and radiological investigations and gave a similar past history. The patient was treated successfully with intravenous medications but two months later developed optic atrophy. An adverse reaction to lignocaine appears to be the most probable cause. Early detection and prompt management of this condition may avert a potentially grave visual outcome. Literature review shows that this case is one of its kinds to report this potentially blinding complication of peribulbar lignocaine anesthesia.
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spelling pubmed-72826852020-06-19 Potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: A rare case report Deshmukh, Saurabh Bhattacharjee, Harsha Gupta, Krati Indian J Pharmacol Drug Watch Peribulbar lignocaine anesthesia is commonly used in ophthalmic surgeries. It rarely causes any severe allergic reaction. A 63-year-old male presented with complicated pseudophakia. He underwent successful vitrectomy under local anesthesia. He later presented with acute-onset proptosis, orbital swelling, and extraocular movement restriction. He was afebrile with normal blood workup and radiological investigations and gave a similar past history. The patient was treated successfully with intravenous medications but two months later developed optic atrophy. An adverse reaction to lignocaine appears to be the most probable cause. Early detection and prompt management of this condition may avert a potentially grave visual outcome. Literature review shows that this case is one of its kinds to report this potentially blinding complication of peribulbar lignocaine anesthesia. Wolters Kluwer - Medknow 2020 2020-06-03 /pmc/articles/PMC7282685/ /pubmed/32565602 http://dx.doi.org/10.4103/ijp.IJP_4_19 Text en Copyright: © 2020 Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Drug Watch
Deshmukh, Saurabh
Bhattacharjee, Harsha
Gupta, Krati
Potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: A rare case report
title Potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: A rare case report
title_full Potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: A rare case report
title_fullStr Potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: A rare case report
title_full_unstemmed Potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: A rare case report
title_short Potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: A rare case report
title_sort potentially blinding adverse drug reaction to peribulbar lignocaine anesthesia: a rare case report
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282685/
https://www.ncbi.nlm.nih.gov/pubmed/32565602
http://dx.doi.org/10.4103/ijp.IJP_4_19
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