Phospho-Ser(784)-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer

Spatiotemporal protein reorganization at DNA damage sites induced by genotoxic chemotherapies is crucial for DNA damage response (DDR), which influences treatment response by directing cancer cell fate. This process is orchestrated by valosin-containing protein (VCP), an AAA+ ATPase that extracts po...

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Detalles Bibliográficos
Autores principales: Zhu, Cuige, Rogers, Anna, Asleh, Karama, Won, Jennifer, Gao, Dongxia, Leung, Samuel, Li, Shan, Vij, Kiran R., Zhu, Jian, Held, Jason M., You, Zhongsheng, Nielsen, Torsten O., Shao, Jieya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282751/
https://www.ncbi.nlm.nih.gov/pubmed/32521270
http://dx.doi.org/10.1016/j.celrep.2020.107745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282751/
https://www.ncbi.nlm.nih.gov/pubmed/32521270
http://dx.doi.org/10.1016/j.celrep.2020.107745

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