Cargando…

Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China

The fight against the novel coronavirus pneumonia (namely COVID-19) that seriously harms human health is a common task for all mankind. Currently, development of drugs against the novel coronavirus (namely SARS-CoV-2) is quite urgent. Chinese medical workers and scientific researchers have found som...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Xiaoqi, Dong, Lan, Yang, Lian, Chen, Dayi, Peng, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282797/
https://www.ncbi.nlm.nih.gov/pubmed/32531236
http://dx.doi.org/10.1016/j.virusres.2020.198057
_version_ 1783544190879137792
author Pan, Xiaoqi
Dong, Lan
Yang, Lian
Chen, Dayi
Peng, Cheng
author_facet Pan, Xiaoqi
Dong, Lan
Yang, Lian
Chen, Dayi
Peng, Cheng
author_sort Pan, Xiaoqi
collection PubMed
description The fight against the novel coronavirus pneumonia (namely COVID-19) that seriously harms human health is a common task for all mankind. Currently, development of drugs against the novel coronavirus (namely SARS-CoV-2) is quite urgent. Chinese medical workers and scientific researchers have found some drugs to play potential therapeutic effects on COVID-19 at the cellular level or in preliminary clinical trials. However, more fundamental studies and large sample clinical trials need to be done to ensure the efficacy and safety of these drugs. The adoption of these drugs without further testing must be careful. The relevant articles, news, and government reports published on the official and Preprint websites, PubMed and China National Knowledge Infrastructure (CNKI) databases from December 2019 to April 2020 were searched and manually filtered. The general pharmacological characteristics, indications, adverse reactions, general usage, and especially current status of the treatment of COVID-19 of those potentially effective drugs, including chemical drugs, traditional Chinese medicines (TCMs), and biological products in China were summarized in this review to guide reasonable medication and the development of specific drugs for the treatment of COVID-19.
format Online
Article
Text
id pubmed-7282797
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-72827972020-06-10 Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China Pan, Xiaoqi Dong, Lan Yang, Lian Chen, Dayi Peng, Cheng Virus Res Article The fight against the novel coronavirus pneumonia (namely COVID-19) that seriously harms human health is a common task for all mankind. Currently, development of drugs against the novel coronavirus (namely SARS-CoV-2) is quite urgent. Chinese medical workers and scientific researchers have found some drugs to play potential therapeutic effects on COVID-19 at the cellular level or in preliminary clinical trials. However, more fundamental studies and large sample clinical trials need to be done to ensure the efficacy and safety of these drugs. The adoption of these drugs without further testing must be careful. The relevant articles, news, and government reports published on the official and Preprint websites, PubMed and China National Knowledge Infrastructure (CNKI) databases from December 2019 to April 2020 were searched and manually filtered. The general pharmacological characteristics, indications, adverse reactions, general usage, and especially current status of the treatment of COVID-19 of those potentially effective drugs, including chemical drugs, traditional Chinese medicines (TCMs), and biological products in China were summarized in this review to guide reasonable medication and the development of specific drugs for the treatment of COVID-19. Elsevier B.V. 2020-09 2020-06-09 /pmc/articles/PMC7282797/ /pubmed/32531236 http://dx.doi.org/10.1016/j.virusres.2020.198057 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Pan, Xiaoqi
Dong, Lan
Yang, Lian
Chen, Dayi
Peng, Cheng
Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China
title Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China
title_full Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China
title_fullStr Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China
title_full_unstemmed Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China
title_short Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China
title_sort potential drugs for the treatment of the novel coronavirus pneumonia (covid-19) in china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282797/
https://www.ncbi.nlm.nih.gov/pubmed/32531236
http://dx.doi.org/10.1016/j.virusres.2020.198057
work_keys_str_mv AT panxiaoqi potentialdrugsforthetreatmentofthenovelcoronaviruspneumoniacovid19inchina
AT donglan potentialdrugsforthetreatmentofthenovelcoronaviruspneumoniacovid19inchina
AT yanglian potentialdrugsforthetreatmentofthenovelcoronaviruspneumoniacovid19inchina
AT chendayi potentialdrugsforthetreatmentofthenovelcoronaviruspneumoniacovid19inchina
AT pengcheng potentialdrugsforthetreatmentofthenovelcoronaviruspneumoniacovid19inchina