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The yeast mating-type switching endonuclease HO is a domesticated member of an unorthodox homing genetic element family

The mating-type switching endonuclease HO plays a central role in the natural life cycle of Saccharomyces cerevisiae, but its evolutionary origin is unknown. HO is a recent addition to yeast genomes, present in only a few genera close to Saccharomyces. Here we show that HO is structurally and phylog...

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Detalles Bibliográficos
Autores principales: Coughlan, Aisling Y, Lombardi, Lisa, Braun-Galleani, Stephanie, Martos, Alexandre AR, Galeote, Virginie, Bigey, Frédéric, Dequin, Sylvie, Byrne, Kevin P, Wolfe, Kenneth H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282813/
https://www.ncbi.nlm.nih.gov/pubmed/32338594
http://dx.doi.org/10.7554/eLife.55336

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