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Cortical microstructural correlates of astrocytosis in autosomal-dominant Alzheimer disease

OBJECTIVE: To study the macrostructural and microstructural MRI correlates of brain astrocytosis, measured with (11)C-deuterium-L-deprenyl ((11)C-DED)–PET, in familial autosomal-dominant Alzheimer disease (ADAD). METHODS: The total sample (n = 31) comprised ADAD mutation carriers (n = 10 presymptoma...

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Detalles Bibliográficos
Autores principales: Vilaplana, Eduard, Rodriguez-Vieitez, Elena, Ferreira, Daniel, Montal, Victor, Almkvist, Ove, Wall, Anders, Lleó, Alberto, Westman, Eric, Graff, Caroline, Fortea, Juan, Nordberg, Agneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282881/
https://www.ncbi.nlm.nih.gov/pubmed/32291295
http://dx.doi.org/10.1212/WNL.0000000000009405

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