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Malignant adenomyoepithelioma of the breast: A case report

INTRODUCTION: Malignant breast adenomyoepithelioma (AME) is a rare subtype of breast cancer. AME is mostly a benign disease that uncommonly undergoes malignant transformation. PRESENTATION OF CASE: Here we present a case of a young, previously healthy female who initially presented with a painless b...

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Autores principales: Lari, Eisa A., Lari, Ali A., Alsaeed, Talal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283092/
https://www.ncbi.nlm.nih.gov/pubmed/32506031
http://dx.doi.org/10.1016/j.ijscr.2020.05.061
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author Lari, Eisa A.
Lari, Ali A.
Alsaeed, Talal
author_facet Lari, Eisa A.
Lari, Ali A.
Alsaeed, Talal
author_sort Lari, Eisa A.
collection PubMed
description INTRODUCTION: Malignant breast adenomyoepithelioma (AME) is a rare subtype of breast cancer. AME is mostly a benign disease that uncommonly undergoes malignant transformation. PRESENTATION OF CASE: Here we present a case of a young, previously healthy female who initially presented with a painless breast lump. The patient underwent wide local excision for atypical cells with squamous metaplasia by core biopsy, but final histopathology showed AME with carcinoma. Thus, a mastectomy and a sentinel lymph node biopsy was undertaken. The patient had an uneventful recovery and no recurrence after the second surgery. DISCUSSION AND CONCLUSION: Malignant transformation of adenomyoepithelioma is reported in a small number of cases. Benign AME may be treated with wide local excision as recurrence is rare locally. Whereas malignant AME tends to be treated with simple mastectomy with or without lymph node biopsy.
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spelling pubmed-72830922020-06-10 Malignant adenomyoepithelioma of the breast: A case report Lari, Eisa A. Lari, Ali A. Alsaeed, Talal Int J Surg Case Rep Article INTRODUCTION: Malignant breast adenomyoepithelioma (AME) is a rare subtype of breast cancer. AME is mostly a benign disease that uncommonly undergoes malignant transformation. PRESENTATION OF CASE: Here we present a case of a young, previously healthy female who initially presented with a painless breast lump. The patient underwent wide local excision for atypical cells with squamous metaplasia by core biopsy, but final histopathology showed AME with carcinoma. Thus, a mastectomy and a sentinel lymph node biopsy was undertaken. The patient had an uneventful recovery and no recurrence after the second surgery. DISCUSSION AND CONCLUSION: Malignant transformation of adenomyoepithelioma is reported in a small number of cases. Benign AME may be treated with wide local excision as recurrence is rare locally. Whereas malignant AME tends to be treated with simple mastectomy with or without lymph node biopsy. Elsevier 2020-05-30 /pmc/articles/PMC7283092/ /pubmed/32506031 http://dx.doi.org/10.1016/j.ijscr.2020.05.061 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lari, Eisa A.
Lari, Ali A.
Alsaeed, Talal
Malignant adenomyoepithelioma of the breast: A case report
title Malignant adenomyoepithelioma of the breast: A case report
title_full Malignant adenomyoepithelioma of the breast: A case report
title_fullStr Malignant adenomyoepithelioma of the breast: A case report
title_full_unstemmed Malignant adenomyoepithelioma of the breast: A case report
title_short Malignant adenomyoepithelioma of the breast: A case report
title_sort malignant adenomyoepithelioma of the breast: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283092/
https://www.ncbi.nlm.nih.gov/pubmed/32506031
http://dx.doi.org/10.1016/j.ijscr.2020.05.061
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