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Malignant adenomyoepithelioma of the breast: A case report
INTRODUCTION: Malignant breast adenomyoepithelioma (AME) is a rare subtype of breast cancer. AME is mostly a benign disease that uncommonly undergoes malignant transformation. PRESENTATION OF CASE: Here we present a case of a young, previously healthy female who initially presented with a painless b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283092/ https://www.ncbi.nlm.nih.gov/pubmed/32506031 http://dx.doi.org/10.1016/j.ijscr.2020.05.061 |
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author | Lari, Eisa A. Lari, Ali A. Alsaeed, Talal |
author_facet | Lari, Eisa A. Lari, Ali A. Alsaeed, Talal |
author_sort | Lari, Eisa A. |
collection | PubMed |
description | INTRODUCTION: Malignant breast adenomyoepithelioma (AME) is a rare subtype of breast cancer. AME is mostly a benign disease that uncommonly undergoes malignant transformation. PRESENTATION OF CASE: Here we present a case of a young, previously healthy female who initially presented with a painless breast lump. The patient underwent wide local excision for atypical cells with squamous metaplasia by core biopsy, but final histopathology showed AME with carcinoma. Thus, a mastectomy and a sentinel lymph node biopsy was undertaken. The patient had an uneventful recovery and no recurrence after the second surgery. DISCUSSION AND CONCLUSION: Malignant transformation of adenomyoepithelioma is reported in a small number of cases. Benign AME may be treated with wide local excision as recurrence is rare locally. Whereas malignant AME tends to be treated with simple mastectomy with or without lymph node biopsy. |
format | Online Article Text |
id | pubmed-7283092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72830922020-06-10 Malignant adenomyoepithelioma of the breast: A case report Lari, Eisa A. Lari, Ali A. Alsaeed, Talal Int J Surg Case Rep Article INTRODUCTION: Malignant breast adenomyoepithelioma (AME) is a rare subtype of breast cancer. AME is mostly a benign disease that uncommonly undergoes malignant transformation. PRESENTATION OF CASE: Here we present a case of a young, previously healthy female who initially presented with a painless breast lump. The patient underwent wide local excision for atypical cells with squamous metaplasia by core biopsy, but final histopathology showed AME with carcinoma. Thus, a mastectomy and a sentinel lymph node biopsy was undertaken. The patient had an uneventful recovery and no recurrence after the second surgery. DISCUSSION AND CONCLUSION: Malignant transformation of adenomyoepithelioma is reported in a small number of cases. Benign AME may be treated with wide local excision as recurrence is rare locally. Whereas malignant AME tends to be treated with simple mastectomy with or without lymph node biopsy. Elsevier 2020-05-30 /pmc/articles/PMC7283092/ /pubmed/32506031 http://dx.doi.org/10.1016/j.ijscr.2020.05.061 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lari, Eisa A. Lari, Ali A. Alsaeed, Talal Malignant adenomyoepithelioma of the breast: A case report |
title | Malignant adenomyoepithelioma of the breast: A case report |
title_full | Malignant adenomyoepithelioma of the breast: A case report |
title_fullStr | Malignant adenomyoepithelioma of the breast: A case report |
title_full_unstemmed | Malignant adenomyoepithelioma of the breast: A case report |
title_short | Malignant adenomyoepithelioma of the breast: A case report |
title_sort | malignant adenomyoepithelioma of the breast: a case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283092/ https://www.ncbi.nlm.nih.gov/pubmed/32506031 http://dx.doi.org/10.1016/j.ijscr.2020.05.061 |
work_keys_str_mv | AT larieisaa malignantadenomyoepitheliomaofthebreastacasereport AT larialia malignantadenomyoepitheliomaofthebreastacasereport AT alsaeedtalal malignantadenomyoepitheliomaofthebreastacasereport |