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An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report
INTRODUCTION: Disseminated intravascular coagulation (DIC) is a blood clotting disorder that is characterized by intravascular thrombi formation and exhaustion of platelets and coagulation factors resulting in diffuse hemorrhage and multiple organ dysfunction. PRESENTATION OF CASE: We present a case...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283093/ https://www.ncbi.nlm.nih.gov/pubmed/32506007 http://dx.doi.org/10.1016/j.ijscr.2020.05.045 |
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author | Kosir, Jurij Ales Salihovic, Mensur Sever, Primoz Klen, Jasna |
author_facet | Kosir, Jurij Ales Salihovic, Mensur Sever, Primoz Klen, Jasna |
author_sort | Kosir, Jurij Ales |
collection | PubMed |
description | INTRODUCTION: Disseminated intravascular coagulation (DIC) is a blood clotting disorder that is characterized by intravascular thrombi formation and exhaustion of platelets and coagulation factors resulting in diffuse hemorrhage and multiple organ dysfunction. PRESENTATION OF CASE: We present a case report of a previously healthy middle-aged patient who was treated by low anterior resection for rectal carcinoma and suddenly went into unexpected circulatory shock on the 7th postoperative day. Despite our resuscitation efforts, he succumbed to the disease. The postmortem examination showed findings consistent with DIC. DISCUSSION: The cause for DIC in this patient may be multifactorial. Sepsis, tumor-related factors and hereditary predisposition may have played a role. The role of blood components in treatment is not fully understood as they may worsen the inflammatory response. CONCLUSION: DIC can be the presenting sign of unrecognized sepsis and it can occur in all surgical patients. Even with prompt treatment, the disease can have a fatal course. |
format | Online Article Text |
id | pubmed-7283093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72830932020-06-10 An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report Kosir, Jurij Ales Salihovic, Mensur Sever, Primoz Klen, Jasna Int J Surg Case Rep Article INTRODUCTION: Disseminated intravascular coagulation (DIC) is a blood clotting disorder that is characterized by intravascular thrombi formation and exhaustion of platelets and coagulation factors resulting in diffuse hemorrhage and multiple organ dysfunction. PRESENTATION OF CASE: We present a case report of a previously healthy middle-aged patient who was treated by low anterior resection for rectal carcinoma and suddenly went into unexpected circulatory shock on the 7th postoperative day. Despite our resuscitation efforts, he succumbed to the disease. The postmortem examination showed findings consistent with DIC. DISCUSSION: The cause for DIC in this patient may be multifactorial. Sepsis, tumor-related factors and hereditary predisposition may have played a role. The role of blood components in treatment is not fully understood as they may worsen the inflammatory response. CONCLUSION: DIC can be the presenting sign of unrecognized sepsis and it can occur in all surgical patients. Even with prompt treatment, the disease can have a fatal course. Elsevier 2020-05-29 /pmc/articles/PMC7283093/ /pubmed/32506007 http://dx.doi.org/10.1016/j.ijscr.2020.05.045 Text en © 2020 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kosir, Jurij Ales Salihovic, Mensur Sever, Primoz Klen, Jasna An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report |
title | An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report |
title_full | An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report |
title_fullStr | An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report |
title_full_unstemmed | An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report |
title_short | An unexpected death after low anterior resection due to disseminated intravascular coagulation: A case report |
title_sort | unexpected death after low anterior resection due to disseminated intravascular coagulation: a case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283093/ https://www.ncbi.nlm.nih.gov/pubmed/32506007 http://dx.doi.org/10.1016/j.ijscr.2020.05.045 |
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