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Degeneration of dopaminergic neurons and impaired intracellular trafficking in Atp13a2 deficient zebrafish

ATP13A2 is the autosomal recessive causative gene for juvenile-onset Parkinson’s disease (PARK9, Parkinson’s disease 9), also known as Kufor-Rakeb syndrome. The disease is characterized by levodopa-responsive Parkinsonism, supranuclear gaze palsy, spasticity, and dementia. Previously, we have report...

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Detalles Bibliográficos
Autores principales: Nyuzuki, Hiromi, Ito, Shinji, Nagasaki, Keisuke, Nitta, Yohei, Matsui, Noriko, Saitoh, Akihiko, Matsui, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283103/
https://www.ncbi.nlm.nih.gov/pubmed/32529115
http://dx.doi.org/10.1016/j.ibror.2020.05.002

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