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Degeneration of dopaminergic neurons and impaired intracellular trafficking in Atp13a2 deficient zebrafish
ATP13A2 is the autosomal recessive causative gene for juvenile-onset Parkinson’s disease (PARK9, Parkinson’s disease 9), also known as Kufor-Rakeb syndrome. The disease is characterized by levodopa-responsive Parkinsonism, supranuclear gaze palsy, spasticity, and dementia. Previously, we have report...
Autores principales: | Nyuzuki, Hiromi, Ito, Shinji, Nagasaki, Keisuke, Nitta, Yohei, Matsui, Noriko, Saitoh, Akihiko, Matsui, Hideaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283103/ https://www.ncbi.nlm.nih.gov/pubmed/32529115 http://dx.doi.org/10.1016/j.ibror.2020.05.002 |
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