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Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN
OBJECTIVE: We tested the hypothesis that exercise training would attenuate metabolic impairment in a model of severe cancer cachexia. METHODS: We used multiple in vivo and in vitro methods to explore the mechanisms underlying the beneficial effects induced by exercise training in tumor-bearing rats....
Autores principales: | Alves, Christiano R.R., Neves, Willian das, de Almeida, Ney R., Eichelberger, Eric J., Jannig, Paulo R., Voltarelli, Vanessa A., Tobias, Gabriel C., Bechara, Luiz R.G., de Paula Faria, Daniele, Alves, Maria J.N., Hagen, Lars, Sharma, Animesh, Slupphaug, Geir, Moreira, José B.N., Wisloff, Ulrik, Hirshman, Michael F., Negrão, Carlos E., de Castro Jr, Gilberto, Chammas, Roger, Swoboda, Kathryn J., Ruas, Jorge L., Goodyear, Laurie J., Brum, Patricia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283151/ https://www.ncbi.nlm.nih.gov/pubmed/32408015 http://dx.doi.org/10.1016/j.molmet.2020.101012 |
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