Co-Regulation of Immune Checkpoint PD-L1 with Interferon-Gamma Signaling is Associated with a Survival Benefit in Renal Cell Cancer

BACKGROUND: Programmed death ligand (PD-L1)-based immune checkpoint blockade therapy for metastatic renal cell carcinoma (RCC) achieves significant response rates in a subgroup of patients. The relevance of PD-L1 gene regulation for disease outcome is not clear. OBJECTIVE: To evaluate PD-L1 expressi...

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Detalles Bibliográficos
Autores principales: Hänze, Jörg, Wegner, Moritz, Noessner, Elfriede, Hofmann, Rainer, Hegele, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283197/
https://www.ncbi.nlm.nih.gov/pubmed/32495158
http://dx.doi.org/10.1007/s11523-020-00728-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283197/
https://www.ncbi.nlm.nih.gov/pubmed/32495158
http://dx.doi.org/10.1007/s11523-020-00728-8

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